Chip based electroanalytical systems for cell analysis

被引:58
作者
Spegel, Christer [3 ]
Heiskanen, Arto [3 ]
Skjolding, Lars Henrik Daehli [2 ]
Emneus, Jenny [1 ]
机构
[1] Tech Univ Denmark DTU Nanotech, Dept Micro & Nanotechnol, DK-2800 Kongens Lyngby, Denmark
[2] Lund Univ, Dept Solid State Phys, S-22100 Lund, Sweden
[3] Lund Univ, Dept Analyt Chem, S-22100 Lund, Sweden
关键词
nondestructive cell analysis; cell impedance; amperometry; microchip; nanoelectrode;
D O I
10.1002/elan.200704130
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for 'nondestructive' measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fiber microelectrodes (CFME) and other nonchip electrode formats, such as CFME for exocytosis studies and scanning electrochemical microscopy (SECM) studies of living cells have been omitted. Included is also a discussion about some future and emerging nano tools and considerations that might have an impact on the future of "nondestructive" chip based electroanalysis of living cells.
引用
收藏
页码:680 / 702
页数:23
相关论文
共 242 条
[1]   Label-free, real-time monitoring of IgE-mediated mast cell activation on microelectronic cell sensor arrays [J].
Abassi, YA ;
Jackson, JA ;
Zhu, J ;
O'Connell, J ;
Wang, XB ;
Xu, X .
JOURNAL OF IMMUNOLOGICAL METHODS, 2004, 292 (1-2) :195-205
[2]   Coordination of cell death and the cell cycle: linking proliferation to death through private and communal couplers [J].
Abrams, JM ;
White, MA .
CURRENT OPINION IN CELL BIOLOGY, 2004, 16 (06) :634-638
[3]   Coupling of electrochemistry and fluorescence microscopy at indium tin oxide microelectrodes for the analysis of single exocytotic events [J].
Amatore, C ;
Arbault, S ;
Chen, Y ;
Crozatier, C ;
Lemaître, F ;
Verchier, Y .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (24) :4000-4003
[4]   Comparison of apex and bottom secretion efficiency at chromaffin cells as measured by amperometry [J].
Amatore, Christian ;
Arbault, Stephane ;
Lemaitre, Frederic ;
Verchier, Yann .
BIOPHYSICAL CHEMISTRY, 2007, 127 (03) :165-171
[5]   Electrochemical detection in a microfluidic device of oxidative stress generated by macrophage cells [J].
Amatore, Christian ;
Arbault, Stephane ;
Chen, Yong ;
Crozatier, Cecile ;
Tapsoba, Issa .
LAB ON A CHIP, 2007, 7 (02) :233-238
[6]   Microtechnologies and nanotechnologies for single-cell analysis [J].
Andersson, H ;
van den Berg, A .
CURRENT OPINION IN BIOTECHNOLOGY, 2004, 15 (01) :44-49
[7]   Microfluidic devices for cellomics: a review [J].
Andersson, H ;
van den Berg, A .
SENSORS AND ACTUATORS B-CHEMICAL, 2003, 92 (03) :315-325
[8]   Cockroach extract antigen increases bronchial airway epithelial permeability [J].
Antony, AB ;
Tepper, RS ;
Mohammed, KA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 110 (04) :589-595
[9]   Bioelectrical impedance assay to monitor changes in cell shape during apoptosis [J].
Arndt, S ;
Seebach, J ;
Psathaki, K ;
Galla, HJ ;
Wegener, J .
BIOSENSORS & BIOELECTRONICS, 2004, 19 (06) :583-594
[10]   Characterization of biological cells by dielectric spectroscopy [J].
Asami, K .
JOURNAL OF NON-CRYSTALLINE SOLIDS, 2002, 305 (1-3) :268-277