Mechanosynthesis of the Metallodrug Bismuth Subsalicylate from Bi2O3 and Structure of Bismuth Salicylate without Auxiliary Organic Ligands

被引：107

作者：

Andre, Vania ^{[2
]}

Hardeman, Andrew ^{[1
]}

Halasz, Ivan ^{[3
]}

Stein, Robin S. ^{[4
]}

Jackson, Graham J. ^{[5
]}

Reid, David G. ^{[1
]}

Duer, Melinda J. ^{[1
]}

Curfs, Caroline ^{[6
]}

Teresa Duarte, M. ^{[2
]}

Friscic, Tomislav ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

[2] Univ Tecn Lisboa, Inst Super Tecn, Ctr Quim Estrutural, P-1100 Lisbon, Portugal

[3] Univ Zagreb, Fac Sci, Dept Chem, Zagreb 41000, Croatia

[4] Bruker UK Ltd, Coventry CV4 9GH, W Midlands, England

[5] Univ Cape Town, Dept Chem, ZA-7700 Rondebosch, South Africa

[6] ESRF ID31, Grenoble, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 34期

基金：

英国生物技术与生命科学研究理事会;

关键词：

bismuth; mechanochemistry; metallodrugs; structure elucidation; sustainable chemistry; MECHANOCHEMICAL SYNTHESIS; STEPWISE MECHANISM; COCRYSTAL; COMPLEXES; REACTIVITY; FRAMEWORKS; CHEMISTRY;

D O I：

10.1002/anie.201103171

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ground out: Mechanochemical methods gave the pharmaceutical ingredient bismuth subsalicylate, as well as bismuth disalicylate and trisalicylate directly from bismuth oxide. Structure determination by powder X-ray diffraction gave the first structure of a bismuth salicylate without auxiliary organic ligands (see picture: Bi yellow, O red, C gray, two salicylate ion coordination modes are shown in purple and green). © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：7858 / 7861

页数：4

共 49 条

[31] Bioinorganic chemistry of bismuth and antimony: Target sites of metallodrugs [J].

Ge, Ruiguang ;

Sun, Hongzhe .

ACCOUNTS OF CHEMICAL RESEARCH, 2007, 40 (04) :267-274

[32]

Guo Z., 1999, Angew. Chem, V111, P1610

[33] Application of Solid-State 209Bi NMR to the Structural Characterization of Bismuth-Containing Materials [J].

Hamaed, Hiyam ;

Laschuk, Michael W. ;

Terskikh, Victor V. ;

Schurko, Robert W. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (23) :8271-8279

[34] Chemical analysis by x-ray diffraction - Classification and use of x-ray diffraction patterns [J].

Hanawalt, JD ;

Rinn, HW ;

Frevel, LK .

INDUSTRIAL AND ENGINEERING CHEMISTRY-ANALYTICAL EDITION, 1938, 10 :0457-0512

[35] QUADRUPOLAR EFFECTS TRANSFERRED TO SPIN-1/2 MAGIC-ANGLE SPINNING SPECTRA OF SOLIDS [J].

HARRIS, RK ;

OLIVIERI, AC .

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 1992, 24 :435-456

[36] SOLID-STATE INTERACTION OF MAGNESIUM-OXIDE AND IBUPROFEN TO FORM A SALT [J].

KARARLI, TT ;

NEEDHAM, TE ;

SEUL, CJ ;

FINNEGAN, PM .

PHARMACEUTICAL RESEARCH, 1989, 6 (09) :804-808

[37] Control and interconversion of cocrystal stoichiometry in grinding: stepwise mechanism for the formation of a hydrogen-bonded cocrystal [J].

Karki, Shyam ;

Friscic, Tomislav ;

Jones, William .

CRYSTENGCOMM, 2009, 11 (03) :470-481

[38] Synthesis of co-crystals of meloxicam with carboxylic acids by grinding [J].

Myz, Svetlana A. ;

Shakhtshneider, Tatyana P. ;

Fucke, Katharina ;

Fedotov, Anatoly P. ;

Boldyreva, Elena V. ;

Boldyrev, Vladimir V. ;

Kuleshova, Nadezhda I. .

MENDELEEV COMMUNICATIONS, 2009, 19 (05) :272-274

[39] Terahertz time-domain spectroscopy and the quantitativemonitoring of mechanochemical cocrystal formation [J].

Nguyen, K. Lien ;

Friscic, Tomislav ;

Day, Graeme M. ;

Gladden, Lynn F. ;

Jones, William .

NATURE MATERIALS, 2007, 6 (03) :206-209

[40] Identification of bismuth-thiolate-carboxylate clusters by electrospray ionization mass spectrometry [J].

Phillips, Heather A. ;

Burford, Neil .

INORGANIC CHEMISTRY, 2008, 47 (07) :2428-2441

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