Functional Cationic Nanomagnet - Porphyrin Hybrids for the Photoinactivation of Microorganisms

被引：110

作者：

Carvalho, Carla M. B. ^{[1
]}

Alves, Eliana ^{[2
]}

Costa, Liliana ^{[2
]}

Tome, Joao P. C. ^{[1
]}

Faustino, Maria A. F. ^{[1
]}

Neves, Maria G. P. M. S. ^{[1
]}

Tome, Augusto C. ^{[1
]}

Cavaleiro, Jose A. S. ^{[1
]}

Almeida, Adelaide ^{[2
]}

Cunha, Angela ^{[2
]}

Lin, Zhi ^{[3
]}

Rocha, Joao ^{[3
]}

机构：

[1] Univ Aveiro, QOPNA, Dept Chem, P-3810193 Aveiro, Portugal

[2] Univ Aveiro, CESAM, Dept Biol, P-3810193 Aveiro, Portugal

[3] Univ Aveiro, CICECO, Dept Chem, P-3810193 Aveiro, Portugal

来源：

ACS NANO | 2010年 / 4卷 / 12期

关键词：

porphyrins; cationic; nanomagnets; photoinactivation; microorganisms; hybrid materials; MAGNETIC NANOPARTICLES; PHOTODYNAMIC THERAPY; WASTE-WATER; INACTIVATION; PHOTOSENSITIZERS; DERIVATIVES; BACTERIA;

D O I：

10.1021/nn1026092

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cationic nanomagnet porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (-) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection.

引用

页码：7133 / 7140

页数：8

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