Palladium-catalyzed cross-coupling reaction of resin-bound chlorotriazines

被引：33

作者：

Bork, JT ^{[1
]}

Lee, JW ^{[1
]}

Chang, YT ^{[1
]}

机构：

[1] NYU, Dept Chem, New York, NY 10003 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(03)01451-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

To introduce the biaryl structure as a triazine functionality, we have developed a new synthetic route via the Suzuki cross-coupling reaction of resin-bound chlorotriazines. The Suzuki cross-coupling reaction was achieved using various arylboronic acids, Pd(PPh3)(4), Cs2CO3, and dioxane. With the integration of this chemistry and our previous orthogonal methodology, the triazine library is greatly expanded to a biaryl scaffold. (C) 2003 Elsevier Ltd. All rights reserved.

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页码：6141 / 6144

页数：4

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