One-pot three-component synthesis of α-amino nitriles catalyzed by nano powder TiO2 P 25

被引:29
作者
Baghbanian, Seyed Meysam [1 ]
Farhang, Maryam [2 ]
Baharfar, Robabeh [2 ]
机构
[1] Islamic Azad Univ, Rasht Branch, Dept Chem, Rasht, Iran
[2] Mazandaran Univ, Dept Chem, Babol Sar 47415, Iran
关键词
Nano powder TiO2 P 25; alpha-Amino nitriles; One-pot three-component synthesis; Strecker reaction; Trimethylsilyl cyanide; STRECKER-TYPE REACTION; FACILE SYNTHESIS; SULFAMIC ACID; EFFICIENT; AMINONITRILES; ALDEHYDES; CONDENSATION; CYANATION; CHLORIDE; KETONES;
D O I
10.1016/j.cclet.2010.12.003
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple and efficient method has been developed for the synthesis of alpha-amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature. (C) 2010 Seyed Meysam Baghbanian. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:555 / 558
页数:4
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