Imidazole and benzimidazole derivatives as chemotherapeutic agents

被引：418

作者：

Boiani, M ^{[1
]}

González, M ^{[1
]}

机构：

[1] Univ Republica, Dept Quim Organ, Fac Ciencias, Fac Quim, Montevideo 11400, Uruguay

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2005年 / 5卷 / 04期

关键词：

D O I：

10.2174/1389557053544047

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Imidazole and benzimidazole systems are presented in a large number of common therapeutics agents. They were widely used in organic and medicinal chemistry, but recently the development of N-oxide derivatives got an improvement from the point of view of its chemical and biological activity. Though we will review recent developments in chemical and biological profiles (as antitumoral, antiparasitic, antiviral and antimicrobial agents) of these heterocycle systems and the corresponding N-oxides.

引用

页码：409 / 424

页数：16

共 137 条

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