Ultrahigh resolution OCT imaging with a two-dimensional MEMS scanning endoscope

被引:4
作者
Aguirre, AD [1 ]
Herz, PR [1 ]
Chen, Y [1 ]
Fujimoto, JG [1 ]
Piyawattanametha, W [1 ]
Fan, L [1 ]
Hsu, ST [1 ]
Fujino, M [1 ]
Wu, MC [1 ]
Kopf, D [1 ]
机构
[1] MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA
来源
Advanced Biomedical and Clinical Diagnostic Systems III | 2005年 / 5692卷
关键词
optical coherence tomography; endoscopy; MEMS;
D O I
10.1117/12.593143
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper reports preliminary results from the development and application of a two-dimensional MEMS endoscopic scanner for OCT imaging. A 1 min diameter mirror provides high aperture over large scan angle and can scan at rates of hundreds of Hz in both axes. The mirror is integrated with focusing optics and a fiber-optic collimator into a package of similar to 5 mm diameter. Using a broadband femtosecond laser light source, ultrahigh axial image resolution of < 5 um in tissue is achieved at 1.06 um center wavelength. Ultrahigh resolution cross-sectional and three-dimensional OCT imaging is demonstrated with the endoscope with similar to 12 um transverse resolution and < 5 um axial resolution.
引用
收藏
页码:277 / 282
页数:6
相关论文
共 20 条
[11]  
PIYAWATTANAMETH.W, 2001, TRANSDUCERS 01 EUROS, V1
[12]   Diagnosis of specialized intestinal metaplasia by optical coherence tomography [J].
Poneros, JM ;
Brand, S ;
Bouma, BE ;
Tearney, GJ ;
Compton, CC ;
Nishioka, NS .
GASTROENTEROLOGY, 2001, 120 (01) :7-12
[13]   Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror [J].
Qi, B ;
Himmer, AP ;
Gordon, LM ;
Yang, XDV ;
Dickensheets, LD ;
Vitkin, IA .
OPTICS COMMUNICATIONS, 2004, 232 (1-6) :123-128
[14]   High-resolution endoscopic imaging of the GI tract using optical coherence tomography [J].
Sivak, MV ;
Kobayashi, K ;
Izatt, JA ;
Rollins, AM ;
Ung-runyawee, R ;
Chak, A ;
Wong, RCK ;
Isenberg, GA ;
Willis, J .
GASTROINTESTINAL ENDOSCOPY, 2000, 51 (04) :474-479
[15]   Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography [J].
Tearney, GJ ;
Boppart, SA ;
Bouma, BE ;
Brezinski, ME ;
Weissman, NJ ;
Southern, JF ;
Fujimoto, JG .
OPTICS LETTERS, 1996, 21 (07) :543-545
[16]   In vivo endoscopic optical biopsy with optical coherence tomography [J].
Tearney, GJ ;
Brezinski, ME ;
Bouma, BE ;
Boppart, SA ;
Pitris, C ;
Southern, JF ;
Fujimoto, JG .
SCIENCE, 1997, 276 (5321) :2037-2039
[17]   Real-time in vivo imaging by high-speed spectral optical coherence tomography [J].
Wojtkowski, M ;
Bajraszewski, T ;
Targowski, P ;
Kowalczyk, A .
OPTICS LETTERS, 2003, 28 (19) :1745-1747
[18]  
YEOM JTW, 2005, SENSOR ACTUAT A-PHYS, V117, P331
[19]   High-speed optical frequency-domain imaging [J].
Yun, SH ;
Tearney, GJ ;
de Boer, JF ;
Iftimia, N ;
Bouma, BE .
OPTICS EXPRESS, 2003, 11 (22) :2953-2963
[20]   Electrostatic micromachine scanning mirror for optical coherence tomography [J].
Zara, JM ;
Yazdanfar, S ;
Rao, KD ;
Izatt, JA ;
Smith, SW .
OPTICS LETTERS, 2003, 28 (08) :628-630