Effect of high hydrostatic pressure and high pressure homogenization on the enantioselectivity of microbial reductions

被引：23

作者：

Fantin, G

Fogagnolo, M

Guerzoni, ME

Lanciotti, R

Medici, A

Pedrini, P

Rossi, D

机构：

[1] UNIV FERRARA,DIPARTIMENTO CHIM,I-44100 FERRARA,ITALY

[2] UNIV BOLOGNA,DPVA,SEZ CHIM & TECNOL ALIMENTI,I-40136 BOLOGNA,ITALY

[3] UNIV BARI,IST PROD & PREPARAZ ALIMENTARI,I-71100 FOGGIA,ITALY

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 10期

关键词：

D O I：

10.1016/0957-4166(96)00379-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The effect of high hydrostatic pressure and high pressure homogenization on the microbial reductions of the model prochiral ketones 1 a-c is described. Various strains of Saccharomyces cerevisiae and Yarrowia lipolytica are utilized in the reduction and higher enantioselectivities are generally achieved together with lower yields compared with the results obtained at atmospheric pressure. In some cases both increasing yields and inversion of enantioselectivity are reported. The effects of the hydrostatic and the homogenization pressure are also compared with the cell viability. Copyright (C) 1996 Elsevier Science Ltd

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页码：2879 / 2887

页数：9

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