Cell division: AAAtacking the mitotic spindle

被引:20
作者
Cheeseman, IM [1 ]
Desai, A [1 ]
机构
[1] Ludwig Inst Canc Res, La Jolla, CA 92093 USA
关键词
D O I
10.1016/j.cub.2003.12.048
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cell division requires the assembly of a microtubule-based spindle which captures and segregates sister chromatids. But how is this spindle broken down once chromosome segregation is complete? New evidence implicates a highly conserved AAA-ATPase in spindle disassembly at the end of mitosis.
引用
收藏
页码:R70 / R72
页数:3
相关论文
共 20 条
  • [1] The spindle checkpoint
    Amon, A
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1999, 9 (01) : 69 - 75
  • [2] Men and sin: What's the difference?
    Bardin, AJ
    Amon, A
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (11) : 815 - 826
  • [3] Cdc48-Ufd1-NpI4: Stuck in the middle with Ub
    Bays, NW
    Hampton, RY
    [J]. CURRENT BIOLOGY, 2002, 12 (10) : R366 - +
  • [4] The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly
    Buvelot, S
    Tatsutani, SY
    Vermaak, D
    Biggins, S
    [J]. JOURNAL OF CELL BIOLOGY, 2003, 160 (03) : 329 - 339
  • [5] The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis
    Cao, K
    Nakajima, R
    Meyer, HH
    Zheng, YX
    [J]. CELL, 2003, 115 (03) : 355 - 367
  • [6] AAA plus proteins and substrate recognition, it all depends on their partner in crime
    Dougan, DA
    Mogk, A
    Zeth, K
    Turgay, K
    Bukau, B
    [J]. FEBS LETTERS, 2002, 529 (01) : 6 - 10
  • [7] PRC1: A human mitotic spindle-associated CDK substrate protein required for cytokinesis
    Jiang, W
    Jimenez, G
    Wells, NJ
    Hope, TJ
    Wahl, GM
    Hunter, T
    Fukunaga, R
    [J]. MOLECULAR CELL, 1998, 2 (06) : 877 - 885
  • [8] APC-mediated proteolysis of Ase 1 and the morphogenesis of the mitotic spindle
    Juang, YL
    Huang, J
    Peters, JM
    McLaughlin, ME
    Tai, CY
    Pellman, D
    [J]. SCIENCE, 1997, 275 (5304) : 1311 - 1314
  • [9] Cell cycle - The mitotic spindle: A self-made machine
    Karsenti, E
    Vernos, I
    [J]. SCIENCE, 2001, 294 (5542) : 543 - 547
  • [10] Microtubule dynamics: New surprises from an old MAP
    McNally, F
    [J]. CURRENT BIOLOGY, 2003, 13 (15) : R597 - R599