Microchip structures for submillisecond electrophoresis

被引:277
作者
Jacobson, SC [1 ]
Culbertson, CT [1 ]
Daler, JE [1 ]
Ramsey, JM [1 ]
机构
[1] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA
关键词
D O I
10.1021/ac980349t
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Microchip electrophoresis was used to resolve a binary mixture in 0.8 ms using a separation field strength of 53 kV cm(-1) and a separation length of 200 mu m. The microchip design permitted an electric field strength of 6.1 V cm(-1) in the separation channel per volt applied to the microchip. Concurrently, the spatial extent of the injection plug and the detector observation region were minimized to increase separation efficiency.
引用
收藏
页码:3476 / 3480
页数:5
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