Stereocontrolled glycosyl transfer reactions with unprotected glycosyl donors

被引：151

作者：

Hanessian, S

Lou, BL

机构：

[1] Univ Montreal, Dept Chem, Stn Ctr Ville, Montreal, PQ H3C 3J7, Canada

[2] Adv SynTech, Louisville, KY 40299 USA

来源：

CHEMICAL REVIEWS | 2000年 / 100卷 / 12期

关键词：

D O I：

10.1021/cr9903454

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A review is given on the methods of O-glycoside synthesis from anomerically activated glycosyl donors in which minimals or no hydroxyl protection is needed. Fisher glycosylation of alcohols is revisited over 100 years later and nature's pathways to glycoside synthesis are emulated albeit with limitations. The concept of remote activation in glycosyl transfer reactions as exemplified by the chemistry of O-unprotected 3-methoxy-2-pyridyloxy (MOP) glycosyl donors is also highlighted.

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页码：4443 / +

页数：22

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