Misunderstandings about isochores. Part 1

被引：94

作者：

Bernardi, G ^{[1
]}

机构：

[1] Staz Zool Anton Dohrn, Lab Mol Evolut, I-80121 Naples, Italy

来源：

GENE | 2001年 / 276卷 / 1-2期

关键词：

genome organization; genome evolution; repeats; mutational bias; gene distribution;

D O I：

10.1016/S0378-1119(01)00644-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A few months ago the International Human Genome Sequencing Consortium (IHGSC) published a 61-page paper on the human genome (IHGSC, Nature 409 (2001) 860). Here comments will be presented on some points of the paper that were previously investigated in our laboratory, and some misunderstandings and misconceptions about the organization and the evolutionary history of the human genome will be discussed. A very recent article on the same subject (Eyre-Walker and Hurst, Nat. Rev. Genet. 2 (2001) 549) will also be addressed. The present paper is a complement to two review articles which were published last year (Bernardi, Gene 241 (2000) 3; Gene 259(1) (2000) 3 1). (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：3 / 13

页数：11

共 73 条

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