Microfluidic operations using deformable polymer membranes fabricated by single layer soft lithography

被引：50

作者：

Sundararajan, N ^{[1
]}

Kim, DS ^{[1
]}

Berlin, AA ^{[1
]}

机构：

[1] Intel Corp, CTM Intel Res, Precis Biol, Santa Clara, CA 95054 USA

来源：

LAB ON A CHIP | 2005年 / 5卷 / 03期

关键词：

D O I：

10.1039/b500792p

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We show that it is possible to use single layer soft lithography to create deformable polymer membranes within microfluidic chips for performing a variety of microfluidic operations. Single layer microfluidic chips were designed, fabricated, and characterized to demonstrate pumping, sorting, and mixing. Flow rates as high as 0.39 mul min(-1) were obtained by peristaltic pumping using pneumatically-actuated membrane devices. Sorting was attained via pneumatic actuation of membrane units placed alongside the branch channels. An active mixer was also demonstrated using single-layer deformable membrane units.

引用

页码：350 / 354

页数：5

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