GaAs pixel arrays for β imaging in medicine and biology

被引:14
作者
Abate, L
Bertolucci, E
Conti, M
Mettivier, G
Montesi, MC
Russo, P
机构
[1] Ist Nazl Fis Nucl, Sez Napoli, I-80126 Naples, Italy
[2] Univ Naples Federico II, Dipartimento Sci Fis, I-80126 Naples, Italy
关键词
autoradiography; beta imaging; pixel detectors; GaAs;
D O I
10.1016/S0168-9002(00)01102-5
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
We present an autoradiography system (BETAview) for a quantitative analysis of radioactive markers in biological samples; this system is also able to monitor a dynamic process. It is based on a solid-state pixel array detector, bump bonded to low threshold, integrated electronics developed for medical applications (Medipix). The present assembly is equipped with a 200 mum thick GaAs square detector, about 1 cm side, segmented into 64 x 64 170-mum size square pixels; simulation and experimental studies show good linearity and high sensitivity to beta sources. Imaging tests with beta sources of medical and biological interest such as C-14, S-35, P-32 reported. (C) 2001 Published by Elsevier Science B.V.
引用
收藏
页码:97 / 106
页数:10
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