We present an autoradiography system (BETAview) for a quantitative analysis of radioactive markers in biological samples; this system is also able to monitor a dynamic process. It is based on a solid-state pixel array detector, bump bonded to low threshold, integrated electronics developed for medical applications (Medipix). The present assembly is equipped with a 200 mum thick GaAs square detector, about 1 cm side, segmented into 64 x 64 170-mum size square pixels; simulation and experimental studies show good linearity and high sensitivity to beta sources. Imaging tests with beta sources of medical and biological interest such as C-14, S-35, P-32 reported. (C) 2001 Published by Elsevier Science B.V.