A novel, one-pot, three-component synthesis of 5H-[1,3]Thiazolo[3,2-a]pyrimidine derivatives

被引：12

作者：

Adib, Mehdi ^{[1
]}

Nosrati, Meisam

Mahdavi, Mohammad

Zhu, Long-Guan

Mirzaei, Peiman

机构：

[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

[3] Shahid Beheshti Univ Med Sci, Dept Chem, Tehran, Iran

来源：

SYNLETT | 2007年 / 17期

关键词：

5H-[1,3]thiazolo[3,2-a]pyrimidines; three-component reaction; isocyanides; cyclizations; heterocycles;

D O I：

10.1055/s-2007-991048

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthesis of highly functionalized 5H-[1,3]thiazolo[3,2-a]pyrimidines is described via a one-pot, three-component addition reaction between isocyanides, dialkyl acetylenedicarboxylates and ethyl 2-oxo-2-(1,3-thiazol-2-ylainino)acetates in good yields.

引用

页码：2703 / 2706

页数：4

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