Desorption electrospray ionization of aerosol particles

被引:16
作者
Dong, Jianan [1 ]
Rezenom, Yohannes H. [1 ]
Murray, Kermit K. [1 ]
机构
[1] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA
关键词
D O I
10.1002/rcm.3294
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We have applied desorption electrospray ionization to aerosol particles. Ions were formed from aerosols by merging suspended dry particles with an electrospray of solvent in a modified ion trap mass spectrometer. Dry aerosol particles were generated using a fluidized bed powder disperser and directed toward the inlet of the mass spectrometer. A nanospray source was used to create a spray of solvent droplets directed at the inlet and at a right angle with respect to the aerosol. Ions generated by the interaction of the particles and electrospray were transferred into the ion trap mass spectrometer. Using this method, pure samples of caffeine and erythromycin A were analyzed. In addition, commonly available food and drug powders including instant cocoa powder, artificial sweetener and ibuprofen were analyzed. Copyright (C) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码:3995 / 4000
页数:6
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