Synthesis of OSW-1 analogues and a dimer and their antitumor activities

被引：49

作者：

Ma, XQ

Yu, B ^{[1
]}

Hui, YZ

Miao, ZH

Ding, J

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 16期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0960-894X(01)00389-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Five analogues, including a 16-epi-isomer (6), and a 3-terephthalic acid linked dimer (8) of OSW-1 were synthesized. Their inhibitory activities on P388 and A-549 cells were detected. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2153 / 2156

页数：4

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