A novel and efficient methodology for the C-C bond forming radical cyclization of hydrophobic substrates in water

被引：97

作者：

Kita, Y ^{[1
]}

Nambu, H ^{[1
]}

Ramesh, NG ^{[1
]}

Anilkumar, G ^{[1
]}

Matsugi, M ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Suita, Osaka 5650871, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 08期

关键词：

D O I：

10.1021/ol010014p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The combination of water-soluble radical initiator 2,2' azobis[2-(2-imidazolin-2-yl)propane] (VA-061), water soluble chain carrier 1-ethylpiperidine hypophosphite (EPHP), and surfactant cetyltrimethylammonium bromide (CTAB) was found to be the most suitable condition for effective radical cyclization in water for a variety of hydrophobic substrates.

引用

页码：1157 / 1160

页数：4

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