Surfing pathogens and the lessons learned for actin polymerization

被引：166

作者：

Frishknecht, F ^{[1
]}

Way, M ^{[1
]}

机构：

[1] European Mol Biol Lab, Cell Biol & Biophys Programme, D-69117 Heidelberg, Germany

来源：

TRENDS IN CELL BIOLOGY | 2001年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0962-8924(00)01871-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A number of unrelated bacterial species as well as vaccinia virus (ab)use the process of actin polymerization to facilitate and enhance their infection cycle. Studies into the mechanism by which these pathogens hijack and control the actin cytoskeleton have provided many interesting insights into the regulation of actin polymerization in migrating cells. This review focuses on what we have learnt from the actin-based motilities of Listeria, Shigella and vaccinia and discusses what we would still like to learn from our nasty friends, including enteropathogenic Escherichia coli and Rickettsia.

引用

页码：30 / 38

页数：9

共 103 条

[1] Separation of membrane trafficking and actin remodeling functions of ARF6 with an effector domain mutant [J].

Al-Awar, O ;

Radhakrishna, H ;

Powell, NN ;

Donaldson, JG .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (16) :5998-6007

[2] Agents that inhibit Rho, Rac, and Cdc42 do not block formation of actin pedestals in HeLa cells infected with enteropathogenic Escherichia coli [J].

Ben-Ami, G ;

Ozeri, V ;

Hanski, E ;

Hofmann, F ;

Aktories, K ;

Hahn, KM ;

Bokoch, GM ;

Rosenshine, I .

INFECTION AND IMMUNITY, 1998, 66 (04) :1755-1758

[3] Interactions between Listeria monocytogenes and host mammalian cells [J].

Braun, L ;

Cossart, P .

MICROBES AND INFECTION, 2000, 2 (07) :803-811

[4] Motility of ActA protein-coated microspheres driven by actin polymerization [J].

Cameron, LA ;

Footer, MJ ;

van Oudenaarden, A ;

Theriot, JA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (09) :4908-4913

[5] Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: Implication in actin-based motility [J].

Carlier, MF ;

Laurent, V ;

Santolini, J ;

Melki, R ;

Didry, D ;

Xia, GX ;

Hong, Y ;

Chua, NH ;

Pantaloni, D .

JOURNAL OF CELL BIOLOGY, 1997, 136 (06) :1307-1322

[6] Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation [J].

Castellano, F ;

Montcourrier, P ;

Guillemot, JC ;

Gouin, E ;

Machesky, L ;

Cossart, P ;

Chavrier, P .

CURRENT BIOLOGY, 1999, 9 (07) :351-360

[7] Functional analysis of a rickettsial OmpA homology domain of Shigella flexneri IcsA [J].

Charles, M ;

Magdalena, J ;

Theriot, JA ;

Goldberg, MB .

JOURNAL OF BACTERIOLOGY, 1999, 181 (03) :869-878

[8] Actin-based motility of pathogens: the Arp2/3 complex is a central player [J].

Cossart, P .

CELLULAR MICROBIOLOGY, 2000, 2 (03) :195-205

[9] Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement:: bacterial factors, cellular ligands and signaling [J].

Cossart, P ;

Lecuit, M .

EMBO JOURNAL, 1998, 17 (14) :3797-3806

[10] ACTIN-BASED MOTILITY OF VACCINIA VIRUS [J].

CUDMORE, S ;

COSSART, P ;

GRIFFITHS, G ;

WAY, M .

NATURE, 1995, 378 (6557) :636-638

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