Detection of 130 nm magnetic particles by a portable electronic platform using spin valve and magnetic tunnel junction sensors

被引:29
作者
Cardoso, F. A. [1 ,2 ]
Germano, J. [2 ,4 ]
Ferreira, R. [1 ,2 ]
Cardoso, S. [1 ,2 ]
Martins, V. C. [1 ,3 ]
Freitas, P. P. [1 ,2 ]
Piedade, M. S. [2 ,4 ]
Sousa, L. [2 ,4 ]
机构
[1] INESC MN, P-1000029 Lisbon, Portugal
[2] Univ Tecn Lisboa, Inst Super Tecn, P-1000029 Lisbon, Portugal
[3] Ctr Biol & Chem Engn CEBQ, Inst Super Tecn, P-1000029 Lisbon, Portugal
[4] INESC ID, P-1000029 Lisbon, Portugal
关键词
D O I
10.1063/1.2836713
中图分类号
O59 [应用物理学];
学科分类号
摘要
An integrated biosensor with magnetic tunnel juntions (MTJs) and spin valve (SV) sensor was used for 130 nm particle detection. A platform drives an external magnet generating an in-plane dc+ac magnetic field on the sensor at frequencies up to 375 Hz, provides a current to bias the sensor, and performs the signal acquisition and treatment. The signal-to-noise ratio of the SV and MTJ was characterized. Bead detection (130 nm in diameter) was performed using both sensors leading to a detection limit of 3 x 10(8) particles/ml for SV and 3 x 10(10) particles/ml for MTJ. (c) 2008 American Institute of Physics.
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页数:3
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