Determination of Bioactive Constituents in Traditional Chinese Medicines by CE with Electrochemical Detection

被引：43

作者：

Chen, Gang ^{[1
]}

Zhu, Yizhun ^{[2
]}

Wang, Yufeng ^{[3
]}

Xu, Xuejiao ^{[1
]}

Lu, Tao ^{[1
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[2] Fudan Univ, Sch Pharm, Shanghai 200032, Peoples R China

[3] Univ Texas San Antonio, Dept Biol, San Antonio, TX 78249 USA

来源：

CURRENT MEDICINAL CHEMISTRY | 2006年 / 13卷 / 21期

关键词：

Traditional Chinese medicine; pharmaceutical analysis; capillary electrophoresis; electrochemical detection; amperometry; electrode; bioactive constituent; differentiation;

D O I：

10.2174/092986706778201657

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper reviews the recent advances and the key strategies in capillary electrophoresis (CE) with electrochemical detection (ECD) for separating and detecting a variety of bioactive constituents in traditional Chinese medicines (TCMs). The subjects covered include the separation modes for the CE analysis of the constituents in TCMs, the CE-ECD system, the sample preparations of TCMs, the ECD of TCMs, the applications of CE-ECD in the determination of various bioactive constituents in Chinese medicinal materials and their preparations, the identification and differentiation of TCMs by CE-ECD, and future prospects. It is expected that CE-ECD will become a powerful tool in the herbal medicinal fields and will lead to the creation of truly routine devices for TCM analysis.

引用

页码：2467 / 2485

页数：19

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