Continuous focus tracking for real-time optical coherence tomography

被引:43
作者
Cobb, MJ [1 ]
Liu, XM [1 ]
Li, XD [1 ]
机构
[1] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA
基金
美国国家科学基金会;
关键词
D O I
10.1364/OL.30.001680
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report an approach to achieving continuous focus tracking and a depth-independent transverse resolution for real-time optical coherence tomography (OCT) imaging. Continuous real-time focus tracking is permitted by use of a lateral-priority image acquisition sequence in which the depth-scanning rate is equivalent to the imaging frame rate. Real-time OCT imaging with continuous focus tracking is performed at 1 frame/s by reciprocal translation of a rapid lateral-scanning miniature imaging probe (e.g., an endoscope). The optical path length in the reference arm is scanned synchronously to ensure that the coherence gate coincides with the imaging beam focus. The image quality improvement is experimentally demonstrated by imaging a tissue phantom embedded with polystyrene microspheres and rabbit esophageal tissues. (c) 2005 Optical Society of America.
引用
收藏
页码:1680 / 1682
页数:3
相关论文
共 12 条
[1]   Dispersion management up to the third order for real-time optical coherence tomography involving a phase or frequency modulator [J].
Chen, YC ;
Li, XD .
OPTICS EXPRESS, 2004, 12 (24) :5968-5978
[2]   Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media [J].
Chen, ZP ;
Milner, TE ;
Dave, D ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (01) :64-66
[3]   In vivo ultrahigh-resolution optical coherence tomography [J].
Drexler, W ;
Morgner, U ;
Kärtner, FX ;
Pitris, C ;
Boppart, SA ;
Li, XD ;
Ippen, EP ;
Fujimoto, JG .
OPTICS LETTERS, 1999, 24 (17) :1221-1223
[4]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[5]  
Lexer F, 1999, J MOD OPTIC, V46, P541, DOI 10.1080/09500349908231282
[6]   Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography [J].
Liu, XM ;
Cobb, MJ ;
Chen, YC ;
Kimmey, MB ;
Li, XD .
OPTICS LETTERS, 2004, 29 (15) :1763-1765
[7]   Quasi in-focus optical coherence tomography [J].
Ohmi, M ;
Kurata, T ;
Sekimoto, M ;
Haruna, M .
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS, 2004, 43 (02) :845-849
[8]   Three dimensional OCT images from retina and skin [J].
Podoleanu, AG ;
Rogers, JA ;
Jackson, DA .
OPTICS EXPRESS, 2000, 7 (09) :292-298
[9]   Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror [J].
Qi, B ;
Himmer, AP ;
Gordon, LM ;
Yang, XDV ;
Dickensheets, LD ;
Vitkin, IA .
OPTICS COMMUNICATIONS, 2004, 232 (1-6) :123-128
[10]   An optical coherence microscope with enhanced resolving power in thick tissue [J].
Schmitt, JM ;
Lee, SL ;
Yung, KM .
OPTICS COMMUNICATIONS, 1997, 142 (4-6) :203-207