Chemoselective biotransformation of nitrites by Rhodococcus equi A4

被引：16

作者：

Martínková, L

Klempier, N

Prepechalová, I

Prikrylová, V

Ovesná, M

Griengl, H

Kren, V

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Lab Biotransformat, CZ-14220 Prague 4, Czech Republic

[2] Graz Tech Univ, Inst Organ Chem, A-8010 Graz, Austria

来源：

BIOTECHNOLOGY LETTERS | 1998年 / 20卷 / 10期

关键词：

D O I：

10.1023/A:1005306723601

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Resting cells of Rhodococcus equi A4 (free or immobilized in hydrogels) produced monomethyl isophtalate 1c and monomethyl terephtalate 2c from methyl-3-cyanobenzoate 1a and methyl-4-cyanobenzoate 2a, respectively, via the intermediate carboxamides 1b and 2b. The use of dried immobilized biocatalysts resulted in an increased formation of the unwanted cyano acids 1d and 2d.

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页码：909 / 912

页数：4

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