Structured three-dimensional optical phantom for optical coherence tomography

被引：46

作者：

Curatolo, Andrea ^{[1
]}

Kennedy, Brendan F. ^{[1
]}

Sampson, David D. ^{[1
,2
]}

机构：

[1] Univ Western Australia, Sch Elect Elect & Comp Engn, Opt Biomed Engn Lab, Crawley, WA 6009, Australia

[2] Univ Western Australia, Ctr Microscopy Characterisat & Anal, Crawley, WA 6009, Australia

来源：

OPTICS EXPRESS | 2011年 / 19卷 / 20期

关键词：

SPECKLE REDUCTION; ELASTOGRAPHY;

D O I：

10.1364/OE.19.019480

中图分类号：

O43 [光学];

学科分类号：

070207 [光学];

摘要：

We present a three-dimensional structured tissue-mimicking phantom for use in optical coherence tomography (OCT). The phantom was fabricated from a silicone matrix and titanium dioxide additive using a lithographic casting method capable of producing a wide range of well-defined geometries with optical contrast and mesoscopic feature sizes relevant to OCT. We describe the fabrication, characterization and OCT imaging of two phantoms and demonstrate their utility in assessing the performance of a spatial-diversity speckle reduction technique. Such phantoms will be important in the development of standards in OCT, as well as in enabling quantitative performance assessment. (C) 2011 Optical Society of America

引用

页码：19480 / 19485

页数：6

共 20 条

[1]

Three-dimensional characterization of optical coherence tomography point spread functions with a nanoparticle-embedded phantom [J].

Agrawal, Anant ;

Pfefer, T. Joshua ;

Gilani, Naureen ;

Drezek, Rebekah .

OPTICS LETTERS, 2010, 35 (13) :2269-2271

[2]

Deformable and durable phantoms with controlled density of scatterers [J].

Bisaillon, Charles-Etienne ;

Lamouche, Guy ;

Maciejko, Romain ;

Dufour, Marc ;

Monchalin, Jean-Pierre .

PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (13) :N237-N247

[3]

Optical phantoms of varying geometry based on thin building blocks with controlled optical properties [J].

de Bruin, Daniel M. ;

Bremmer, Rolf H. ;

Kodach, Vitali M. ;

de Kinkelder, Roy ;

van Marle, Jan ;

van Leeuwen, Ton G. ;

Faber, Dirk J. .

JOURNAL OF BIOMEDICAL OPTICS, 2010, 15 (02)

[4]

Speckle reduction in OCT using massively-parallel detection and frequency-domain ranging [J].

Desjardins, A. E. ;

Vakoc, B. J. ;

Tearney, G. J. ;

Bouma, B. E. .

OPTICS EXPRESS, 2006, 14 (11) :4736-4745

[5]

Design, fabrication, and characterization of a tissue-equivalent phantom for optical elastography [J].

Devi, CU ;

Vasu, RM ;

Sood, AK .

JOURNAL OF BIOMEDICAL OPTICS, 2005, 10 (04)

[6]

Detection of multiple scattering in optical coherence tomography by speckle correlation of angle-dependent B-scans [J].

Hillman, Timothy R. ;

Curatolo, Andrea ;

Kennedy, Brendan F. ;

Sampson, David D. .

OPTICS LETTERS, 2010, 35 (12) :1998-2000

[7]

OPTICAL COHERENCE TOMOGRAPHY [J].

HUANG, D ;

SWANSON, EA ;

LIN, CP ;

SCHUMAN, JS ;

STINSON, WG ;

CHANG, W ;

HEE, MR ;

FLOTTE, T ;

GREGORY, K ;

PULIAFITO, CA ;

FUJIMOTO, JG .

SCIENCE, 1991, 254 (5035) :1178-1181

[8]

In vivo three-dimensional optical coherence elastography [J].

Kennedy, Brendan F. ;

Liang, Xing ;

Adie, Steven G. ;

Gerstmann, Derek K. ;

Quirk, Bryden C. ;

Boppart, Stephen A. ;

Sampson, David D. .

OPTICS EXPRESS, 2011, 19 (07) :6623-6634

[9]

Fibrin phantom for use in optical coherence tomography [J].

Kennedy, Brendan F. ;

Loitsch, Susanne ;

McLaughlin, Robert A. ;

Scolaro, Loretta ;

Rigby, Paul ;

Sampson, David D. .

JOURNAL OF BIOMEDICAL OPTICS, 2010, 15 (03)

[10]

Speckle reduction in optical coherence tomography by strain compounding [J].

Kennedy, Brendan F. ;

Hillman, Timothy R. ;

Curatolo, Andrea ;

Sampson, David D. .

OPTICS LETTERS, 2010, 35 (14) :2445-2447

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