Synthesis of tertiary α-amino phosphonate by one-pot three-component coupling mediated by LPDE

被引：86

作者：

Azizi, N ^{[1
]}

Saidi, MR ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON | 2003年 / 59卷 / 28期

关键词：

tertiary alpha-amino phosphonate; trialkylphosphite; lithium perchlorate;

D O I：

10.1016/S0040-4020(03)00759-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A very mild, efficient and simple method for the synthesis of tertiary alpha-amino phosphonates is reported by reaction of an aldehyde, a secondary amine and trialkylphosphite in ethereal solution of lithium perchlorate, LPDE, at ambient temperature with high yields. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：5329 / 5332

页数：4

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