Synthesis of tertiary α-amino phosphonate by one-pot three-component coupling mediated by LPDE

被引:86
作者
Azizi, N [1 ]
Saidi, MR [1 ]
机构
[1] Sharif Univ Technol, Dept Chem, Tehran, Iran
关键词
tertiary alpha-amino phosphonate; trialkylphosphite; lithium perchlorate;
D O I
10.1016/S0040-4020(03)00759-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A very mild, efficient and simple method for the synthesis of tertiary alpha-amino phosphonates is reported by reaction of an aldehyde, a secondary amine and trialkylphosphite in ethereal solution of lithium perchlorate, LPDE, at ambient temperature with high yields. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5329 / 5332
页数:4
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