How filamentous pathogens co-opt plants: the ins and outs of fungal effectors

被引:175
作者
de Jonge, Ronnie [1 ]
Bolton, Melvin D. [2 ]
Thomma, Bart P. H. J. [1 ,3 ]
机构
[1] Wageningen Univ, Phytopathol Lab, NL-6708 PB Wageningen, Netherlands
[2] ARS, USDA, No Crop Sci Lab, Fargo, ND USA
[3] Ctr BioSyst Genom, NL-6700 AB Wageningen, Netherlands
关键词
GENE-EXPRESSION; VIRULENCE; PROTEIN; HOST; CELLS; SUSCEPTIBILITY; TRANSLOCATION; RECOGNITION; METABOLISM; PROTEASES;
D O I
10.1016/j.pbi.2011.03.005
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Research on effectors secreted by pathogens during host attack has dominated the field of molecular plant-microbe interactions over recent years. Functional analysis of type Ill secreted effectors injected by pathogenic bacteria into host cells has significantly advanced the field and demonstrated that many function to suppress host defense. Fungal and oomycete effectors are delivered outside the host plasma membrane, and although research has lagged behind on bacterial effectors, we are gradually learning more and more about the functions of these effectors. While some function outside the host cell to disarm defense, others exploit host cellular uptake mechanisms-to suppress defense or liberate nutrients intracellularly. Comparative genomics suggests that the organization of effector genes drives effector evolution in many pathogen genomes.
引用
收藏
页码:400 / 406
页数:7
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