A tetrahedron-based inhomogeneous Monte Carlo optical simulator

被引：99

作者：

Shen, H. ^{[1
]}

Wang, G. ^{[1
]}

机构：

[1] Virginia Tech, Sch Biomed Engn & Sci, Blacksburg, VA 24061 USA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2010年 / 55卷 / 04期

关键词：

HIGHLY SCATTERING TISSUES; LIGHT TRANSPORT; SPHERICAL-HARMONICS; BIOLOGICAL TISSUE; PROPAGATION; TOMOGRAPHY; BIOLUMINESCENCE; MOUSE; MODEL; DISTRIBUTIONS;

D O I：

10.1088/0031-9155/55/4/003

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Optical imaging has been widely applied in preclinical and clinical applications. Fifteen years ago, an efficient Monte Carlo program 'MCML' was developed for use with multi-layered turbid media and has gained popularity in the field of biophotonics. Currently, there is an increasingly pressing need for simulating tools more powerful than MCML in order to study light propagation phenomena in complex inhomogeneous objects, such as the mouse. Here we report a tetrahedron-based inhomogeneous Monte Carlo optical simulator (TIM-OS) to address this issue. By modeling an object as a tetrahedron-based inhomogeneous finite-element mesh, TIM-OS can determine the photon-triangle interaction recursively and rapidly. In numerical simulation, we have demonstrated the correctness and efficiency of TIM-OS.

引用

页码：947 / 962

页数：16

共 52 条

[1] GEANT4-a simulation toolkit [J].

Agostinelli, S ;

Allison, J ;

Amako, K ;

Apostolakis, J ;

Araujo, H ;

Arce, P ;

Asai, M ;

Axen, D ;

Banerjee, S ;

Barrand, G ;

Behner, F ;

Bellagamba, L ;

Boudreau, J ;

Broglia, L ;

Brunengo, A ;

Burkhardt, H ;

Chauvie, S ;

Chuma, J ;

Chytracek, R ;

Cooperman, G ;

Cosmo, G ;

Degtyarenko, P ;

Dell'Acqua, A ;

Depaola, G ;

Dietrich, D ;

Enami, R ;

Feliciello, A ;

Ferguson, C ;

Fesefeldt, H ;

Folger, G ;

Foppiano, F ;

Forti, A ;

Garelli, S ;

Giani, S ;

Giannitrapani, R ;

Gibin, D ;

Cadenas, JJG ;

González, I ;

Abril, GG ;

Greeniaus, G ;

Greiner, W ;

Grichine, V ;

Grossheim, A ;

Guatelli, S ;

Gumplinger, P ;

Hamatsu, R ;

Hashimoto, K ;

Hasui, H ;

Heikkinen, A ;

Howard, A .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2003, 506 (03) :250-303

[2] Tetrahedral elements in self-consistent parallel 3D Monte Carlo simulations of MOSFETs [J].

Aldegunde, M. ;

Garcia-Loureiro, A. J. ;

Martinez, A. ;

Kalna, K. .

JOURNAL OF COMPUTATIONAL ELECTRONICS, 2008, 7 (03) :201-204

[3]

Alerstam E., 2009, CUDAMCML-User manual and implementation notes

[4] Parallel computing with graphics processing units for high-speed Monte Carlo simulation of photon migration [J].

Alerstam, Erik ;

Svensson, Tomas ;

Andersson-Engels, Stefan .

JOURNAL OF BIOMEDICAL OPTICS, 2008, 13 (06)

[5] Geant4 developments and applications [J].

Allison, J ;

Amako, K ;

Apostolakis, J ;

Araujo, H ;

Dubois, PA ;

Asai, M ;

Barrand, G ;

Capra, R ;

Chauvie, S ;

Chytracek, R ;

Cirrone, GAP ;

Cooperman, G ;

Cosmo, G ;

Cuttone, G ;

Daquino, GG ;

Donszelmann, M ;

Dressel, M ;

Folger, G ;

Foppiano, F ;

Generowicz, J ;

Grichine, V ;

Guatelli, S ;

Gumplinger, P ;

Heikkinen, A ;

Hrivnacova, I ;

Howard, A ;

Incerti, S ;

Ivanchenko, V ;

Johnson, T ;

Jones, F ;

Koi, T ;

Kokoulin, R ;

Kossov, M ;

Kurashige, H ;

Lara, V ;

Larsson, S ;

Lei, F ;

Link, O ;

Longo, F ;

Maire, M ;

Mantero, A ;

Mascialino, B ;

McLaren, I ;

Lorenzo, PM ;

Minamimoto, K ;

Murakami, K ;

Nieminen, P ;

Pandola, L ;

Parlati, S ;

Peralta, L .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2006, 53 (01) :270-278

[6]

[Anonymous], P SPIE IS

[7]

[Anonymous], 2009, INT MATH KERN LIB RE

[8] A FINITE-ELEMENT APPROACH FOR MODELING PHOTON TRANSPORT IN TISSUE [J].

ARRIDGE, SR ;

SCHWEIGER, M ;

HIRAOKA, M ;

DELPY, DT .

MEDICAL PHYSICS, 1993, 20 (02) :299-309

[9] Optical tomography in medical imaging [J].

Arridge, SR .

INVERSE PROBLEMS, 1999, 15 (02) :R41-R93

[10] Light transport in tissue by 3D Monte Carlo:: Influence of boundary voxelization [J].

Binzoni, T. ;

Leung, T. S. ;

Giust, R. ;

Ruefenach, D. ;

Gandjbakhche, A. H. .

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2008, 89 (01) :14-23

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