Vinylogous nitroaldol (Henry) reaction using 3,5-diethyl-4-nitroisoxazole and carbonyl compounds

被引：21

作者：

Adamo, Mauro F. A. ^{[1
]}

Suresh, Surisetti ^{[1
]}

机构：

[1] Royal Coll Surgeons Ireland, Dept Pharmaceut & Med Chem, CSCB, Dublin 2, Ireland

来源：

TETRAHEDRON | 2009年 / 65卷 / 05期

关键词：

4-Nitroisoxazoles; Henry reaction; Vinylogous nitroaldol; ASYMMETRIC MICHAEL ADDITION; ENZYMATIC ALDOL REACTION; TRIGGERED PRO-MITOSENE; MULTICOMPONENT SYNTHESIS; CINCHONA ORGANOCATALYSTS; ACIDS; STYRYLISOXAZOLES; NITROALKENES; ALKALOIDS; CATALYSIS;

D O I：

10.1016/j.tet.2008.11.089

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,5-Diethyl-4-nitroisoxazole reacted with carbonyl compounds in the presence of an amine catalyst. The vinylogous nitroaldol adducts were isolated in good yields. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：990 / 997

页数：8

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