Solvent-Induced High Fidelity Switching Between Two Discrete Supramolecules

被引：46

作者：

Betancourt, Jose E. ^{[1
]}

Martin-Hidalgo, Mariana ^{[1
]}

Gubala, Vladimir ^{[1
]}

Rivera, Jose M. ^{[1
]}

机构：

[1] Univ Puerto Rico, Dept Chem, Rio Piedras, PR 00931 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 09期

关键词：

DIRECT NMR DETECTION; 2'-DEOXYGUANOSINE DERIVATIVES; CATION-BINDING; DIFFUSION NMR; INTERCONVERSION; CHEMISTRY; EXCHANGE; INSIGHTS; RELEASE; IONS;

D O I：

10.1021/ja809612d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we show the reversible high fidelity switching between two discrete self-assembled supramolecules made from a lipophilic 8-phenyl-2'-deoxyguanosine derivative induced by an indirect solvent effect. A hexadecameric supramolecule containing four stacked tetramers, is formed in acetonitrile aided by higher potassium concentrations. When the amount of weakly solvated potassium decreases, due the lower activity of potassium iodide in chloroform, an octamer is formed after the dissociation of the two outer tetramers in the hexadecamer. The switching process results from an unprecedented subtle interplay between the activity of potassium iodide and the steric crowding within the self-assembled structure. Besides the possible applications in nanoconstruction, this phenomenon sheds light into the mechanism of formation of self-assembled supramolecules made from guanosine derivatives.

引用

页码：3186 / +

页数：5

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