Ruthenium-Catalyzed Synthesis of Functionalized Dienes from Propargylic Esters: Formal Cross-Coupling of Two Carbenes

被引：52

作者：

Bray, Chloe Vovard-Le ^{[1
]}

Derien, Sylvie ^{[1
]}

Dixneuf, Pierre H. ^{[1
]}

机构：

[1] Univ Rennes 1, CNRS, UMR 6226, Inst Sci Chim Rennes,Lab Catalyse & Organomet, F-35042 Rennes, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 08期

关键词：

carbenes; catalysis; cross-coupling; dienes; ruthenium; OPENING METATHESIS POLYMERIZATION; RING CLOSING METATHESIS; CYCLOISOMERIZATION REACTIONS; TERMINAL ALKYNES; ENYNES; DIMERIZATION; CYCLOPROPANATION; CONSTRUCTION; COMPLEXES; DIENYNES;

D O I：

10.1002/anie.200805031

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cross-coupling carbenes: The coupling of a propargylic ester with a diazoalkane in the presence of [RuCl(cod)Cp*] catalyst leads to the formation of functionalized conjugated dienes with high stereoselectivity. The reactioninvolves the cross-coupling of a vinylcarbene fragment, arising from a ruthenium-catalyzed propargylic ester rearrangement, with a diazoalkane carbene. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1439 / 1442

页数：4

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