Recent advances in capillary electrophoretic analysis of individual cells

被引：32

作者：

Arcibal, Imee G. ^{[1
]}

Santillo, Michael F. ^{[1
]}

Ewing, Andrew G. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2007年 / 387卷 / 01期

关键词：

single-cell analysis; cell sampling; capillary electrophoresis;

D O I：

10.1007/s00216-006-0690-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Because variability exists within populations of cells, single-cell analysis has become increasingly important for probing complex cellular environments. Capillary electrophoresis (CE) is an excellent technique for identifying and quantifying the contents of single cells owing to its small volume requirements and fast, efficient separations with highly sensitive detection. Recent progress in both whole-cell and subcellular sampling has allowed researchers to study cellular function in the areas of neuroscience, oncology, enzymology, immunology, and gene expression.

引用

页码：51 / 57

页数：7

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