Microarray data processing and analysis

被引:9
作者
Dopazo, J [1 ]
机构
[1] Spanish Natl Canc Ctr, Bioinformat Unit, Madrid 28029, Spain
来源
METHODS OF MICROARRAY DATA ANALYSIS II | 2002年
关键词
gene expression; normalisation; databases; distances; clustering; gene networks; data mining;
D O I
10.1007/0-306-47598-7_4
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
DNA arrays technologies make possible the monitoring of changes in the expression patterns of thousands of genes. The analysis of such data has become a computationally-intensive task that requires technological developments at various stages, from the design of the array, to image analysis, database storage, data processing and clustering and information extraction. Here a review of the current trends in each of the various areas is provided.
引用
收藏
页码:43 / 63
页数:21
相关论文
共 86 条
[21]  
CUMMINGS CA, 2001, BRIEFINGS BIOINFORMA, V2, P402
[22]   Genetic network inference: from co-expression clustering to reverse engineering [J].
D'haeseleer, P ;
Liang, SD ;
Somogyi, R .
BIOINFORMATICS, 2000, 16 (08) :707-726
[23]   Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays [J].
Der, SD ;
Zhou, AM ;
Williams, BRG ;
Silverman, RH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (26) :15623-15628
[24]   Methods and approaches in the analysis of gene expression data [J].
Dopazo, J ;
Zanders, E ;
Dragoni, I ;
Amphlett, C ;
Falciani, F .
JOURNAL OF IMMUNOLOGICAL METHODS, 2001, 250 (1-2) :93-112
[25]   Phylogenetic reconstruction using an unsupervised growing neural network that adopts the topology of a phylogenetic tree [J].
Dopazo, J ;
Carazo, JM .
JOURNAL OF MOLECULAR EVOLUTION, 1997, 44 (02) :226-233
[26]   DNAPROBE, a computer program which generates oligonucleotide probes from protein alignments [J].
Drummond, M ;
Stamper, J .
NUCLEIC ACIDS RESEARCH, 1999, 27 (17) :3493-3493
[27]   STATISTICAL-DATA ANALYSIS IN THE COMPUTER-AGE [J].
EFRON, B ;
TIBSHIRANI, R .
SCIENCE, 1991, 253 (5018) :390-395
[28]   Cluster analysis and display of genome-wide expression patterns [J].
Eisen, MB ;
Spellman, PT ;
Brown, PO ;
Botstein, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (25) :14863-14868
[29]   Correspondence analysis applied to microarray data [J].
Fellenberg, K ;
Hauser, NC ;
Brors, B ;
Neutzner, A ;
Hoheisel, JD ;
Vingron, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (19) :10781-10786
[30]   Using Bayesian networks to analyze expression data [J].
Friedman, N ;
Linial, M ;
Nachman, I ;
Pe'er, D .
JOURNAL OF COMPUTATIONAL BIOLOGY, 2000, 7 (3-4) :601-620