A highly practical and enantioselective reagent for the allylation of aldehydes

被引:130
作者
Kubota, K [1 ]
Leighton, JL [1 ]
机构
[1] Columbia Univ, Dept Chem, New York, NY 10027 USA
关键词
D O I
10.1002/anie.200390252
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Strain at silicon is the key to success of reagent 1 since this strain, which is induced by the diazasilacyclopentane ring, determines its reactivity. This practical and general new reagent for the highly enantioselective allylation of aldehydes is easily prepared as an air-stable solid and may be stored without significant decomposition.
引用
收藏
页码:946 / +
页数:4
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