Efficient Synthesis of Aryl Fluorides

被引：82

作者：

Anbarasan, Pazhamalai ^{[1
]}

Neumann, Helfried ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 12期

关键词：

aryl fluorides; aryl halides; electrophilic fluorination; Grignard reagents; N-F reagents; CROSS-COUPLING REACTIONS; PALLADIUM-CATALYZED HYDROXYLATION; GRIGNARD-REAGENTS; FUNCTIONALIZED ARYLMAGNESIUM; MAGNESIUM-EXCHANGE; ALKYL-HALIDES; FLUORINATION; IRON; COMPLEXES; HALOGEN;

D O I：

10.1002/anie.200905855

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemical Equation Presented" Creating C-F bonds: A novel electrophilic fluorination of aryl and heteroaryl Crignard reagents has been discovered and was used for the efficient synthesis of various aryl fluoride derivatives (see picture; THF = tetrahydrofuran). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA."

引用

页码：2219 / 2222

页数：4

共 68 条

[41] Catalytic C-C, C-N, and C-O Ullmann-Type Coupling Reactions
Monnier, Florian
Taillefer, Marc
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (38) : 6954 - 6971
[42] Practical palladium catalysts for C-N and C-O bond formation
Muci, AR
Buchwald, SL
[J]. CROSS-COUPLING REACTIONS: A PRACTICAL GUIDE, 2002, 219 : 131 - 209
[43] An Efficient and Practical Sequential One-Pot Synthesis of Suprofen, Ketoprofen and Other 2-Arylpropionic Acids
Neumann, Helfried
Brennfuehrer, Anne
Beller, Matthias
[J]. ADVANCED SYNTHESIS & CATALYSIS, 2008, 350 (14-15) : 2437 - 2442
[44] Nicolaou K.C., 2005, Angew. Chem, V117, P4516, DOI DOI 10.1002/ANGE.200500368
[45] Palladium-catalyzed cross-coupling reactions in total synthesis
Nicolaou, KC
Bulger, PG
Sarlah, D
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (29) : 4442 - 4489
[46] Biaryls made easy: PEPPSI and the Kumada-Tamao-Corriu reaction
Organ, Michael G.
Abdel-Hadi, Mirvat
Avola, Stephanie
Hadei, Niloufar
Nasielski, Joanna
O'Brien, Christopher J.
Valente, Cory
[J]. CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (01) : 150 - 157
[47] The influence of fluorinated molecules (semiochemicals and enzyme substrate analogues) on the insect communication system
Pesenti, C
Viani, F
[J]. CHEMBIOCHEM, 2004, 5 (05) : 590 - 613
[48] Positron emission tomography provides molecular imaging of biological processes
Phelps, ME
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (16) : 9226 - 9233
[49] Halex reactions of aromatic compounds catalysed by 2-azaallenium, carbophosphazenium, aminophosphonium and diphosphazenium salts:: a comparative study
Pleschke, A
Marhold, A
Schneider, M
Kolomeitsev, A
Röschenthaler, GN
[J]. JOURNAL OF FLUORINE CHEMISTRY, 2004, 125 (06) : 1031 - 1038
[50] Bimetallic Pd(III) complexes in palladium-catalysed carbon-heteroatom bond formation
Powers, David C.
Ritter, Tobias
[J]. NATURE CHEMISTRY, 2009, 1 (04) : 302 - 309

← 1 2 3 4 5 6 7 →