Contribution of Radiation Hybrids to Genome Mapping in Domestic Animals

被引:15
作者
Faraut, T. [1 ]
de Givry, S. [1 ]
Hitte, C. [2 ]
Lahbib-Mansais, Y. [1 ]
Morisson, M. [1 ]
Milan, D. [1 ]
Schiex, T. [1 ]
Servin, B. [1 ]
Vignal, A. [1 ]
Galibert, F. [2 ]
Yerle, M. [1 ]
机构
[1] INRA, Lab Genet Cellulaire & Biometrie & Intelligence A, F-31326 Castanet Tolosan, France
[2] Univ Rennes, Inst Genet & Dev Rennes, Rennes, France
关键词
Comparative mapping; Domestic animals; Genome maps; Radiation hybrid maps; Radiation hybrid panel; PORCINE SOMATIC-CELL; RESOLUTION COMPARATIVE MAP; RH MAP; REDUCED REPRESENTATION; STATISTICAL-METHODS; CHICK ERYTHROCYTES; HUMAN-CHROMOSOMES; FRAMEWORK MAP; SNP DISCOVERY; PHYSICAL MAP;
D O I
10.1159/000245904
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Radiation hybrid mapping has emerged in the end of the 1990s as a successful and complementary approach to map genomes, essentially because of its ability to bridge the gaps between genetic and clone-based physical maps, but also using comparative mapping approaches, between 'generich' and 'gene-poor' maps. Since its early development in human, radiation hybrid mapping played a pivotal role in the process of mapping animal genomes, especially mammalian ones. We review here all the different steps involved in radiation hybrid mapping from the constitution of panels to the construction of maps. A description of its contribution to whole genome maps with a special emphasis on domestic animals will also be presented. Finally, current applications of radiation hybrid mapping in the context of whole genome assemblies will be described. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码:21 / 33
页数:13
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