Palladium-catalyzed three-component synthesis of 3-(diarylmethylene)oxindoles through a domino Sonagashira/carbopalladation/C-H activation/C-C bond-forming sequence

被引：190

作者：

Pinto, Artur ^{[1
]}

Neuville, Luc ^{[1
]}

Zhu, Jieping ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 18期

关键词：

C-H activation; domino reactions; multicomponent reactions; nitrogen heterocycles; palladium;

D O I：

10.1002/anie.200605192

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) 3-3-1 Formation: [Pd(PPh3) 4]/Cul serves as an efficient catalyst for the reaction of three readily available starting materials to give 3-(diarylmethylene)indolin-2-ones 3 through a sequence of intermolecular Sonagashira reaction/intermolecular carbopalladation/C-H activation/C-C bond formation (see scheme). Three C-C bonds are thereby formed as a result of three distinct catalytic cycles with one catalyst. DMF = N,N-dimethylformamide. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3291 / 3295

页数：5

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