Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics

被引：82

作者：

Roberts, MC ^{[1
]}

机构：

[1] Univ Washington, Sch Publ Hlth & Community Med, Dept Pathobiol, Seattle, WA 98195 USA

来源：

MOLECULAR BIOTECHNOLOGY | 2004年 / 28卷 / 01期

关键词：

macrolide; lincosamide; streptogramin; ketolide; oxazolidinone; resistance;

D O I：

10.1385/MB:28:1:47

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Macrolides have enjoyed a resurgence as new derivatives and related compounds have come to market. These newer compounds have become important in the treatment of community-acquired pneumoniae and nontuberculosis-Mycobacterium diseases. In this review, the bacterial mechanisms of resistance to the macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics, the distribution of the various acquired genes that confer resistance, as well as mutations that have been identified in clinical and laboratory strains are examined.

引用

页码：47 / 62

页数：16

共 114 条

[101] In vitro activity of PNU-100766 (linezolid), a new oxazolidinone antimicrobial, against Nocardia brasiliensis [J].

Vera-Cabrera, L ;

Gómez-Flores, A ;

Escalante-Fuentes, WG ;

Welsh, O .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (12) :3629-3630

[102] Macrolide resistance conferred by base substitutions in 23S rRNA [J].

Vester, B ;

Douthwaite, S .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (01) :1-12

[103] Use of clindamycin disks to detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and children [J].

Waites, K ;

Johnson, C ;

Gray, B ;

Edwards, K ;

Crain, M ;

Benjamin, W .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (05) :1731-1734

[104] The importance of efflux pumps in bacterial antibiotic resistance [J].

Webber, MA ;

Piddock, LJV .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (01) :9-11

[105] ERYTHROMYCIN RESISTANCE BY RIBOSOME MODIFICATION [J].

WEISBLUM, B .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (03) :577-585

[106] Emergence of the M phenotype of erythromycin-resistant Pneumococci in South Africa [J].

Widdowson, CA ;

Klugman, KP .

EMERGING INFECTIOUS DISEASES, 1998, 4 (02) :277-281

[107] Efficacy of linezolid versus comparator therapies in Gram-positive infections [J].

Wilcox, MH .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 :27-35

[108] Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by real-time PCR and PCR-restriction fragment length polymorphism analysis [J].

Woodford, N ;

Tysall, L ;

Auckland, C ;

Stockdale, MW ;

Lawson, AJ ;

Walker, RA ;

Livermore, DM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) :4298-4300

[109] Gonorrhea among men who have sex with men:: Outbreak caused by a single genotype of erythromycin-resistant Neisseria gonorrhoeae with a single-base pair deletion in mtrR promoter region [J].

Xia, MS ;

Whittington, WLH ;

Shafer, WM ;

Holmes, KK .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (06) :2080-2082

[110] Mutations in the GTPase center of Escherichia coli 23S rRNA indicate release factor 2-interactive sites [J].

Xu, WB ;

Pagel, FT ;

Murgola, EJ .

JOURNAL OF BACTERIOLOGY, 2002, 184 (04) :1200-1203

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