Advances in NMR-based biofluid analysis and metabolite profiling

被引:84
作者
Zhang, Shucha [1 ]
Gowda, G. A. Nagana [1 ]
Ye, Tao [1 ]
Raftery, Daniel [1 ]
机构
[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
关键词
NUCLEAR-MAGNETIC-RESONANCE; TOTAL CORRELATION SPECTROSCOPY; RESIDUAL WATER SUPPRESSION; RESEARCH-AND-DEVELOPMENT; INDIRECT COVARIANCE NMR; HUMAN AMNIOTIC-FLUID; H-1-NMR SPECTROSCOPY; DATA SETS; ENVIRONMENTAL METABOLOMICS; INFORMATION RECOVERY;
D O I
10.1039/c000091d
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Significant improvements in NMR technology and methods have propelled NMR studies to play an important role in a rapidly expanding number of applications involving the profiling of metabolites in biofluids. This review discusses recent technical advances in NMR spectroscopy based metabolite profiling methods, data processing and analysis over the last three years.
引用
收藏
页码:1490 / 1498
页数:9
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