Large-scale production of oligosaccharides using engineered bacteria

被引:72
作者
Endo, T [1 ]
Koizumi, S [1 ]
机构
[1] Kyowa Hakko Kogyo Co Ltd, Tokyo Res Labs, Tokyo 1948533, Japan
关键词
D O I
10.1016/S0959-440X(00)00127-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Rapid advances in the cloning and expression of glycosyltransferase genes, especially from bacteria, could open the way to overcoming difficulties in the mass production of oligosaccharides. The large-scale production of oligosaccharides using either glycosyltransferases isolated from engineered microorganisms or whole cells as an enzyme source could promote a new era in the field of carbohydrate synthesis.
引用
收藏
页码:536 / 541
页数:6
相关论文
共 49 条
  • [1] On the preparative use of recombinant pig α(1-3)galactosyl-transferase
    Baisch, G
    Öhrlein, R
    Kolbinger, F
    Streiff, M
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (12) : 1575 - 1578
  • [2] On the preparative use of recombinant β(1-3)galactosyl-transferase
    Baisch, G
    Öhrlein, R
    Streiff, M
    Kolbinger, F
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (07) : 751 - 754
  • [3] Enzymatic synthesis of sialyl-Lewis-libraries with two nonnatural monosaccharide units
    Baisch, G
    Öhrlein, R
    Streiff, M
    Kolbinger, F
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (07) : 755 - 758
  • [4] The living factory:: In vivo production of N-acetyllactosamine containing carbohydrates in E-coli
    Bettler, E
    Samain, E
    Chazalet, V
    Bosso, C
    Heyraud, A
    Joziasse, DH
    Wakarchuk, WW
    Imberty, A
    Geremia, RA
    [J]. GLYCOCONJUGATE JOURNAL, 1999, 16 (03) : 205 - 212
  • [5] High-level expression of the Neisseria meningitidis lgtA gene in Escherichia coli and characterization of the encoded N-acetylglucosaminyltransferase as a useful catalyst in the synthesis of GlcNAcβ1→3Gal and GalNAcβ1-3Gal linkages
    Blixt, O
    van Die, I
    Norberg, T
    van den Eijnden, DH
    [J]. GLYCOBIOLOGY, 1999, 9 (10) : 1061 - 1071
  • [6] SCALED-UP EXPRESSION OF HUMAN ALPHA-2,6(N)SIALYLTRANSFERASE IN SACCHAROMYCES-CEREVISIAE
    BORSIG, L
    IVANOV, SX
    HERRMANN, GF
    KRAGL, U
    WANDREY, C
    BERGER, EG
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 210 (01) : 14 - 20
  • [7] Structure/function studies of glycosyltransferases
    Breton, C
    Imberty, A
    [J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 1999, 9 (05) : 563 - 571
  • [8] Enzymatic synthesis of nucleotide sugars
    Bülter, T
    Elling, L
    [J]. GLYCOCONJUGATE JOURNAL, 1999, 16 (02) : 147 - 159
  • [9] Glycosidases and glycosyl transferases in glycoside and oligosaccharide synthesis
    Crout, DHG
    Vic, G
    [J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 1998, 2 (01) : 98 - 111
  • [10] Glycobiology: Toward understanding the function of sugars
    Dwek, RA
    [J]. CHEMICAL REVIEWS, 1996, 96 (02) : 683 - 720