Noise characteristics and particle detection limits in diode plus MTJ matrix elements for biochip applications

被引：11

作者：

Cardoso, F. A. ^{[1
]}

Ferreira, R.

Cardoso, S.

Conde, J. P.

Chu, V.

Freitas, P. P.

Germano, J.

Almeida, T.

Sousa, L.

Piedade, M. S.

机构：

[1] INESC MN, P-1000029 Lisbon, Portugal

[2] IST, P-1000029 Lisbon, Portugal

[3] INESC ID, P-1000029 Lisbon, Portugal

来源：

IEEE TRANSACTIONS ON MAGNETICS | 2007年 / 43卷 / 06期

关键词：

DNA-chips; magnetic nanoparticles; magnetic tunnel junction; magnetoresistive biochips;

D O I：

10.1109/TMAG.2007.893705

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A fully scalable matrix-based magnetoresistive biochip has been recently introduced for the detection of biomolecular recognition events. This work reports results for a 3 x 3 cells matrix comprising hydrogenated amorphous silicon diodes (PIN and Schottky) and aluminum oxide magnetic tunnel junctions (MTJ). The noise characteristics of the individual thin film diodes (TFD) and the MTJ were analyzed for measuring frequencies from DC to 1 kHz, allowing the detection of single magnetic nanoparticles with 250 mn and 130 nm diameters. For 50 nm particles, and at 1 kHz, minimum number of detectable labels ranges from 20 (Schottky diodes) to 50 (PIN diodes).

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收藏

页码：2403 / 2405

页数：3

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