Asymmetric allylic substitution catalyzed by palladium-Yliphos complex

被引：30

作者：

Ohta, T ^{[1
]}

Sasayama, H ^{[1
]}

Nakajima, O ^{[1
]}

Kurahashi, N ^{[1
]}

Fujii, T ^{[1
]}

Furukawa, I ^{[1
]}

机构：

[1] Doshisha Univ, Fac Engn, Dept Mol Sci & Technol, Kyoto 6100394, Japan

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(03)00046-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Allylic substitution reactions catalyzed by Pd- or Pt-Yliphos complexes are examined. The reaction of 1,3-diphenyl-2-propenyl acetate with benzylamine proceeded in the presence of Pd(dba)(2)-Yliphos to give N-benzyl-1,3-diphenyl-2-propenylamine in high yields with high enantioselectivities (up to 90% ee). Furthermore, the allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate catalyzed by Pd-Yliphos complex resulted in high enantioselectivity (95% ee) in the presence of LiH as base. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：537 / 542

页数：6

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