ROLE OF HETEROTRIMERIC GTP-BINDING PROTEINS IN VESICULAR PROTEIN-TRANSPORT - INDICATIONS FOR BOTH CLASSICAL AND ALTERNATIVE G-PROTEIN CYCLES

被引：76

作者：

HELMS, JB

机构：

来源：

FEBS LETTERS | 1995年 / 369卷 / 01期

关键词：

HETEROTRIMERIC GTP BINDING PROTEIN; VESICULAR TRAFFICKING; SIGNAL TRANSDUCTION; GOLGI APPARATUS; SECRETORY PATHWAY; ENDOCYTIC PATHWAY;

D O I：

10.1016/0014-5793(95)00620-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Heterotrimeric G proteins are involved in hormonal signal transduction across the plasma membrane. Recent evidence suggests that they have a role in vesicular protein transport as well, Biochemical probes that interfere with the classical G protein cycle have been applied to the field of intracellular membrane transport to study their mechanism of action. Evidence has been obtained that intracellular G proteins act both through classical and alternative G protein cycles.

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页码：84 / 88

页数：5

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