ENZYMES IN ORGANIC-SYNTHESIS .14. KINETIC RESOLUTION OF ALIPHATIC 1,2-DIOLS BY A LIPASE-CATALYZED SEQUENTIAL ACETYLATION

被引：37

作者：

THEIL, F

WEIDNER, J

BALLSCHUH, S

KUNATH, A

SCHICK, H

机构：

[1] Centre of Selective Organic Synthesis, D(O)- 1199 Berlin-Adlershof

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)60573-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The kinetic resolution of 13 racemic aliphatic 1,2-diols (rac-1a-m) by means of a lipase-catalyzed sequential acetylation was investigated. The enantioselectivity of the 3-aryloxy-propane-1,2-diols rac-1a-k depends on the substitution pattern at the aryl ring.

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页码：305 / 306

页数：2

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