MOLECULAR-CLONING OF A NOVEL CALCIUM-BINDING PROTEIN STRUCTURALLY RELATED TO HIPPOCALCIN FROM HUMAN BRAIN AND CHROMOSOMAL MAPPING OF ITS GENE

被引：16

作者：

KOBAYASHI, M

TAKAMATSU, K

FUJISHIRO, M

SAITOH, S

NOGUCHI, T

机构：

[1] TOHO UNIV,SCH MED,DEPT PHYSIOL,OHTA KU,TOKYO 143,JAPAN

[2] TOMY SEIKO CORP,DIV RES & DEV,NERIMA KU,TOKYO 176,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 1994年 / 1222卷 / 03期

关键词：

CLONING; NUCLEOTIDE SEQUENCE; CHROMOSOMAL MAPPING; HIPPOCALCIN-LIKE PROTEIN; BRAIN; (HUMAN);

D O I：

10.1016/0167-4889(94)90062-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA clone (hHLP2) encoding a novel calcium-binding protein structurally related to hippocalcin has been isolated from the human hippocampus cDNA library. The primary structure consists of 193 amino acids, and contains three EF-hand structures and a possible NH2-terminal myristoylation site. A single transcript at a position corresponding to 1.7 kilobases was detected only in the brain. The hHLP2 gene was mapped to human chromosome 2.

引用

页码：515 / 518

页数：4

共 17 条

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