Digital self-referencing quantitative phase microscopy by wavefront folding in holographic image reconstruction

被引：78

作者：

Coppola, G. ^{[1
]}

Di Caprio, G. ^{[1
]}

Gioffre, M. ^{[1
]}

Puglisi, R. ^{[2
]}

Balduzzi, D. ^{[2
]}

Galli, A.

Miccio, L. ^{[3
]}

Paturzo, M. ^{[3
]}

Grilli, S. ^{[3
]}

Finizio, A. ^{[3
]}

Ferraro, P. ^{[3
]}

机构：

[1] CNR Ist Microelettron & Microsistemi, I-80131 Naples, Italy

[2] Ist Sperimentale Italiano Lazzaro Spallanzani, I-26027 Rivolta Dadda, Cremona, Italy

[3] Ist Nazl Ottica, CNR, Sez Napoli, I-80078 Naples, Italy

来源：

OPTICS LETTERS | 2010年 / 35卷 / 20期

关键词：

MICROFLUIDIC DEVICES; CONTRAST MICROSCOPY;

D O I：

10.1364/OL.35.003390

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A completely numerical method, named digital self-referencing holography, is described to easily accomplish a quantitative phase microscopy for microfluidic devices by a digital holographic microscope. The approach works through an appropriate numerical manipulation of the retrieved complex wavefront. The self-referencing is obtained by folding the retrieved wavefront in the image plane. The folding operation allows us to obtain the correct phase map by subtracting from the complex region of interest a flat area outside the microfluidic channel. To demonstrate the effectiveness of the method, quantitative phase maps of bovine spermatozoa and in vitro cells are retrieved. (C) 2010 Optical Society of America

引用

页码：3390 / 3392

页数：3

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