Theoretical and experimental validation of treatment planning for narrow MLC defined photon fields

被引:20
作者
Lydon, JM [1 ]
机构
[1] Radiat Oncol Victoria, Melbourne, Vic 3002, Australia
关键词
D O I
10.1088/0031-9155/50/11/018
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In intensity modulated radiotherapy (IMRT), the use of small fields where electronic equilibrium does not exist is becoming more common and presents difficulties for both the measurement and calculation of dose to such fields. Pinnacle(3) (Version 6.2b) allows the user to specify a total minimum open area for each IMRT segment, which can result in sub-segments with widths of only a few millimetres. The dose for 6 MV narrow MLC defined fields between 0.1 and 3 cm in width was investigated using Kodak extended dose range film (EDR2), ionization chamber and MOSFET dosimeters and BEAMnrc Monte Carlo calculations, and these results were used to determine the accuracy of Pinnacle3 dose calculation for narrow MLC segments. The incident fluences calculated by Pinnacle 3 and BEAMnrc were also compared. Results show that if a fluence and dose grid resolution of 0.1 cm is used, Pinnacle3 dose agrees with the EDR2 and BEAMnrc to within 5% for field widths between 0.5 and 3.0 cm. However, Pinnacle(3) will underestimate the dose by up to 45% for the 0.1 and 0.3 cm wide fields. It is shown that the source size in the Pinnacle 3 beam model and both the fluence and dose grid resolutions have a significant effect on the accuracy of dose calculation for field widths of 1.0 cm and less. For single segment fields, Pinnacle(3) agrees with EDR2 and BEAMnrc to within 0.1 cm at the field edges and underestimates the penumbra width by up to 0.08 cm. Results for multiple segment fields showed that an MLC transmission of 1.7% and a 0.06 cm inward shift of MLCs prior to beam delivery gave the closest agreement between Pinnacle 3 and measurement. The multiple segment fields also revealed a pattern of low dose troughs of up to 7% in the Pinnacle3 dose profiles.
引用
收藏
页码:2701 / 2714
页数:14
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