A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

被引:157
作者
Masanta, Goutam [2 ,3 ]
Heo, Cheol Ho [2 ,3 ]
Lim, Chang Su [1 ]
Bae, Sung Keun [2 ,3 ]
Cho, Bong Rae [1 ]
Kim, Hwan Myung [2 ,3 ]
机构
[1] Korea Univ, Dept Chem, Seoul 136701, South Korea
[2] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea
[3] Ajou Univ, Mol Sci & Technol Res Ctr, Suwon 443749, South Korea
关键词
OXIDATIVE STRESS; BIOLOGY;
D O I
10.1039/c2cc00034b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H2O2 in live cells and intact tissues at > 100 mu m depth through the use of two-photon microscopy.
引用
收藏
页码:3518 / 3520
页数:3
相关论文
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