Pseudoceratinazole A: a novel bromotyrosine alkaloid from the Australian sponge Pseudoceratina sp.

被引:17
作者
Feng, Yunjiang [1 ]
Davis, Rohan A. [1 ]
Sykes, Melissa L. [1 ]
Avery, Vicky M. [1 ]
Camp, David [1 ]
Quinn, Ronald J. [1 ]
机构
[1] Griffith Univ, Eskitis Inst, Brisbane, Qld 4111, Australia
关键词
AEROTHIONIN;
D O I
10.1016/j.tetlet.2010.07.052
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Mass-directed fractionation based on a Trypanosoma brucei brucei active fraction from the Australian sponge Pseudoceratina sp. led to the isolation of a novel bromotyrosine alkaloid, pseudoceratinazole A (1). Compound 1 is the first dimeric bromotyrosine alkaloid containing an imidazole-bridging moiety. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4847 / 4850
页数:4
相关论文
共 24 条
[1]  
ANDERSEN RJ, 1973, TETRAHEDRON LETT, P1175
[2]  
[Anonymous], 2009, Dictionary of Natural Products Version 18.2
[3]   Bromotyrosine alkaloids from the sponge Pseudoceratina verrucosa [J].
Benharref, A ;
Pais, M ;
Debitus, C .
JOURNAL OF NATURAL PRODUCTS, 1996, 59 (02) :177-180
[4]   Psammaplysenes C and D, cytotoxic alkaloids from Psammoclemma sp. [J].
Buchanan, Malcolm S. ;
Carroll, Anthony R. ;
Addepalli, Rama ;
Avery, Vicky M. ;
Hooper, John N. A. ;
Quinn, Ronald J. .
JOURNAL OF NATURAL PRODUCTS, 2007, 70 (11) :1827-1829
[5]   Antimalarial Benzylisoquinoline Alkaloid from the Rainforest Tree Doryphora sassafras [J].
Buchanan, Malcolm S. ;
Davis, Rohan A. ;
Duffy, Sandra ;
Avery, Vicky M. ;
Quinn, Ronald J. .
JOURNAL OF NATURAL PRODUCTS, 2009, 72 (08) :1541-1543
[6]   Chemistry of verongida sponges .8. Bromocompounds from the Mediterranean sponges Aplysina aerophoba and Aplysina cavernicola [J].
Ciminiello, P ;
Fattorusso, E ;
Forino, M ;
Magno, S ;
Pansini, M .
TETRAHEDRON, 1997, 53 (18) :6565-6572
[7]   11-deoxyfistularin-3, a new cytotoxic metabolite from the caribbean sponge Aplysina fistularis insularis [J].
Compagnone, RS ;
Avila, R ;
Suárez, AI ;
Abrams, OV ;
Rangel, HR ;
Arvelo, F ;
Piña, IC ;
Merentes, E .
JOURNAL OF NATURAL PRODUCTS, 1999, 62 (10) :1443-1444
[8]   (+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp. [J].
Davis, Rohan A. ;
Duffy, Sandra ;
Avery, Vicky M. ;
Camp, David ;
Hooper, John N. A. ;
Quinn, Ronald J. .
TETRAHEDRON LETTERS, 2010, 51 (04) :583-585
[9]   Marine natural products [J].
Faulkner, DJ .
NATURAL PRODUCT REPORTS, 2002, 19 (01) :1-48
[10]   Antitrypanosomal pyridoacridine alkaloids from the Australian ascidian Polysyncraton echinatum [J].
Feng, Yunjiang ;
Davis, Rohan A. ;
Sykes, Melissa L. ;
Avery, Vicky M. ;
Carroll, Anthony R. ;
Camp, David ;
Quinn, Ronald J. .
TETRAHEDRON LETTERS, 2010, 51 (18) :2477-2479