Novel cytotoxic annonaceous acetogenins from Annona muricata

被引：70

作者：

Chang, FR ^{[1
]}

Wu, YC ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 07期

关键词：

D O I：

10.1021/np010035s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Seven new annonaceous acetogenins, muricins A-G (1-7), as well as five known compounds, a mixture of muricatetrocin A (8) and muricatetrocin B (9), longifolicin (10), corossolin (11), and corossolone (12), were isolated from the seeds of Annona muricata. The structures of all isolates were elucidated and characterized by spectral and chemical methods. These acetogenins showed significantly selective in vitro cytotoxicities toward the human hepatoma cell lines Hep G(2) and 2,2,15.

引用

页码：925 / 931

页数：7

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